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Symbol Name ID |
Irs2
insulin receptor substrate 2 MGI:109334 |
| Darker colors indicate more annotations |
| Mouse Phenotypes | decreased oocyte number |
decreased granulosa cell proliferation |
abnormal corpus luteum morphology |
absent corpus luteum |
abnormal ovarian follicle morphology |
absent mature ovarian follicles |
decreased primary ovarian follicle number |
decreased tertiary ovarian follicle number |
increased atretic ovarian follicle number |
abnormal ovarian folliculogenesis |
impaired ovarian folliculogenesis |
polyovular ovarian follicle |
small ovary |
abnormal oogenesis |
failure of superovulation |
anovulation |
prolonged diestrus |
absent estrous cycle |
prolonged estrous cycle |
female infertility |
reduced female fertility |
reduced male fertility |
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| Availability | Mouse Genotype | ||||||||||||||||||||||
| Irs2tm1.1With/Irs2tm1.1With | |||||||||||||||||||||||
| Irs2tm1Mfw/Irs2tm1Mfw | |||||||||||||||||||||||
| Irs2tm1With/Irs2tm1With Tg(Nes-cre)1Kln/? (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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